Global Health Data Exchange - Discover the World's Health Data

United States Framingham Heart Study Original Cohort


General Info
Coverage type 
Time period covered 
01/1948 - present
Series or system 
United States Framingham Heart Study (FHS)
Data type
  • Exam
  • Household
  • Individual
  • Interview
  • Longitudinal

The Framingham Heart Study (FHS) has been in existence since 1948. Initially, the longitudinal project included 5,209 men and women, ages 30-62, from the town of Framingham, Massachusetts. Participants return every two years for a medical history, physical examination, and laboratory tests. In 1971, the study enrolled 5,124 of the original participants' adult children and their spouses. In 1994, the Omni cohort, 506 men and women of African-American, Hispanic, Asian, Indian, Pacific Islander and Native American descent, was enrolled. Since 2002, a third generation, second Omni group, and New Offspring Spouse cohort have been added, and as the study continues, new cohorts are enrolled. The study includes demographic information, risk factors, medical history, and mental and physical status. The examinations include blood tests, urine tests, ECGs, spirometry, tonometry, echocardiograms, and others. The results are later analyzed for patterns related to CVD development.

Abortion, Abortive outcome, Adult mortality, Adverse effects of medical treatments, Aged adults, Alcohol use, Alzheimer's disease and other dementias, Amputation, Analgesics, Anemia, Anthropometry, Antibiotics, Antihypertensive drugs, Anxiety, Aortic aneurysm, Asthma, Atrial fibrillation and flutter, Back pain, Biopsy, Birth place, Birth weight, Bladder cancer, Blood disorders, Blood glucose, Blood pressure, Body mass index, Bone mineral density, Brain and nervous system cancers, Breast cancer, Breathing difficulty, COPD, Calcium, Cancers, Cardiomyopathies, Cardiovascular and circulatory diseases, Cardiovascular surgical procedures, Cataracts, Cerebrovascular diseases, Cervix uteri cancer, Child mortality, Cholesterol, Cholesterol tests, Chronic kidney diseases, Chronic respiratory diseases, Claudication, Clinical breast exams, Cognitive assessment, Cohort study, Colon and rectum cancers, Conduction disorders and other dysrhythmias, Congenital anomalies, Congenital heart anomalies, Congestion, Corpus uteri cancer, Corrective lenses, Cough, Dairy products, Decubitus ulcer, Diabetes, Diet, Digital rectal examinations, Diphtheria, Disability, Drug consumption, Eclampsia, Edema, Education, Electrocardiograms, Emergency care, Employment, Eye examinations, Falls, Family composition, Family size, Fatigue, Fertility, Fever, Fruits, Gall bladder and bile duct disease, Gallbladder and biliary tract cancers, General surgery, Glaucoma, Glucose tests, Gout, Headache, Health care use, Health insurance, Health status, Hearing aids, Hearing loss, Hearing tests, Heart disease, Heart failure, Height, Hemoglobin, Hemorrhagic stroke, Hodgkin lymphoma, Home care, Hormone replacement therapy, Hospitals, Household deaths, Hypercholesterolemia, Hypertension, Hypertensive disorders of pregnancy, Hypertriglyceridemia, ICD-O-1, ICD-O-3, Incontinence, Infant mortality, Infectious diseases, Influenza, Injuries, Insulin, Interventions, Iron, Iron supplements, Ischemic heart disease, Jaundice, Kidney and other urinary organ cancers, Languages, Larynx cancer, Leisure activities, Length of stay, Leukemia, Lifestyle risk factors, Limited mobility, Live births, Liver cancer, Living conditions, Lower respiratory infections, Macular degeneration, Marital status, Meat, Medicines, Menopause, Menstruation, Mental health symptoms, Micronutrient supplements, Military service, Milk, Mobility aids, Mortality, Mouth cancer, Musculoskeletal diseases, Nausea, Neurological conditions, Non-Hodgkin lymphoma, Nursing homes, Nutrition, Nuts, Obesity, Occult blood, Occupational risk factors, Occupations, Oesophagus cancer, Oral conditions, Osteoarthritis, Outpatient facilities, Ovary cancer, Pain, Pancreas cancer, Parental survival, Parents, Parkinson's disease, Peptic ulcer disease, Peripheral vascular diseases, Pharynx cancers, Physical activity, Physical examinations, Place of death, Polio, Pregnancy complications, Prescriptions, Processed foods, Processed meats, Prostate cancer, Prostheses and implants, Pulse, Refraction and accommodation disorders, Rehabilitation, Respiratory function tests, Respiratory infections, Rheumatic heart disease, Rheumatoid arthritis, Sense organ diseases, Sibling survival, Siblings, Skin cancers, Sleep, Stomach cancer, Stroke, Sugar-sweetened beverages, Suicide, Sun exposure, Symptoms, Thoracic surgery, Thyroid gland disorders, Tobacco, Tobacco smoking, Trachea, bronchus, and lung cancers, Tuberculosis, Unintentional injuries, Unipolar depressive disorders, Unprocessed red meat, Upper respiratory infections, Urinary diseases, Urine tests, Urolithiasis, Vascular insufficiency of intestine, Vegetables, Vision loss, Vitamin A supplements, Vomiting, Weight, Weight change, Whole grains, X-rays, Zinc