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United States Framingham Heart Study Offspring Cohort


General Info
Coverage type 
Time period covered 
01/1971 - present
Series or system 
United States Framingham Heart Study (FHS)
Data type
  • Exam
  • Household
  • Individual
  • Interview
  • Longitudinal

The Framingham Heart Study (FHS) has been in existence since 1948. Initially, the longitudinal project included 5,209 men and women, ages 30-62, from the town of Framingham, Massachusetts. Participants return every two years for a medical history, physical examination, and laboratory tests. In 1971, the study enrolled 5,124 of the original participants' adult children and their spouses. In 1994, the Omni cohort, 506 men and women of African-American, Hispanic, Asian, Indian, Pacific Islander and Native American descent, was enrolled. Since 2002, a third generation, second Omni group, and New Offspring Spouse cohort have been added, and as the study continues, new cohorts are enrolled. The study includes demographic information, risk factors, medical history, and mental and physical status. The examinations include blood tests, urine tests, ECGs, spirometry, tonometry, echocardiograms, and others. The results are later analyzed for patterns related to CVD development.

Adult mortality, Adverse effects of medical treatments, Alcohol use, Alcohol use disorders, Allergies, Alzheimer's disease and other dementias, Amputation, Analgesics, Anthropometry, Antibiotics, Antihypertensive drugs, Anxiety, Anxiety disorders, Aortic aneurysm, Asthma, Back pain, Birth control pills, Bladder cancer, Blood disorders, Blood glucose, Blood pressure, Blood tests, Body mass index, Brain and nervous system cancers, Breast cancer, Breathing difficulty, COPD, Calcium, Caloric intake, Cardiomyopathies, Cardiovascular and circulatory diseases, Cardiovascular surgical procedures, Cerebrovascular diseases, Cervix uteri cancer, Cholesterol, Cholesterol tests, Chronic kidney diseases, Chronic respiratory diseases, Cirrhosis of the liver, Clinical breast exams, Cohort study, Colon and rectum cancers, Colonoscopy, Complete birth history, Conduction disorders and other dysrhythmias, Congenital heart anomalies, Congestion, Contraceptive implants, Contraceptives, Cough, Dairy products, Death certificates, Decubitus ulcer, Dentists, Diabetes, Diet, Digital rectal examinations, Disability, Drug consumption, Edema, Education, Electrocardiograms, Emergency care, Employment, Endocrine disorders, Epilepsy, Ethnicity, Eye examinations, Falls, Family composition, Fish, Folic acid supplements, Fruits, Gall bladder and bile duct disease, Gallbladder and biliary tract cancers, General surgery, Glucose tests, Gout, Gynecological diseases, Health care use, Health insurance, Health status, Hearing aids, Hearing loss, Hearing tests, Heart disease, Heart failure, Height, Hemoglobin, Hemorrhagic stroke, Home care, Hormone replacement therapy, Hospitals, Hours worked, Hypercholesterolemia, Hypertension, Hypothyroidism, Hysterectomy, ICD-O-1, ICD-O-2, ICD-O-3, Income, Incontinence, Injectable contraceptives, Injuries, Insulin, Interventions, Iodine supplements, Iron, Iron supplements, Ischemic heart disease, Kidney and other urinary organ cancers, Larynx cancer, Legumes, Length of stay, Leukemia, Lifestyle risk factors, Limited mobility, Literacy, Live births, Living conditions, Lower respiratory infections, Marital status, Meat, Medicines, Menopause, Menstruation, Mental and behavioral disorders, Mental health symptoms, Micronutrient supplements, Micronutrients, Military service, Milk, Mobility aids, Mortality, Mouth cancer, Musculoskeletal diseases, Neurological conditions, Non-Hodgkin lymphoma, Nurses, Nursing homes, Nutrition, Nuts, Obesity, Occult blood, Occupational risk factors, Occupations, Oesophagus cancer, Osteoarthritis, Ovary cancer, Pain, Pancreas cancer, Pap smears, Parental survival, Parents, Parkinson's disease, Peptic ulcer disease, Peripheral vascular diseases, Pharynx cancers, Physical activity, Physical examinations, Place of death, Prescriptions, Processed foods, Processed meats, Prostate cancer, Prostheses and implants, Pulse, Race, Refraction and accommodation disorders, Respiratory function tests, Respiratory infections, Rheumatic heart disease, Rheumatoid arthritis, SF-12, SF-36, Screening mammography, Secondhand smoke, Seizures, Sense organ diseases, Sexual sterilization, Sibling survival, Siblings, Skin cancers, Skin diseases, Sleep, Sleep disorders, Starchy vegetables, Stomach cancer, Stool tests, Stroke, Sugar-sweetened beverages, Suicide, Teachers, Thoracic surgery, Thyroid gland disorders, Tobacco, Tobacco smoking, Trachea, bronchus, and lung cancers, Unipolar depressive disorders, Unprocessed red meat, Upper respiratory infections, Urinary diseases, Urine tests, Urolithiasis, Vegetables, Vision loss, Vitamin A supplements, Vitamin D supplements, Weight, Weight change, Whole grains, X-rays, Zinc