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Kenya - Nyanza Global Enteric Multicenter Study 2011-2012


General Info
Original or alternative title 
Global Enteric Multi-Center Study / GEMS-1A
Kenya (KEN)
Coverage type 
Time period covered 
10/2011 - 12/2012
Series or system 
Global Enteric Multicenter Study (GEMS)
Data type
  • Exam
  • Health facility
  • Household
  • Individual
  • Interview

The Global Enteric Multicenter Study (GEMS) was a multi-country case-control study of diarrheal diseases in children under five years of age. GEMS-1A was a follow-up to the original GEMS-1 study, and took place in all of the original seven sites in Africa and Asia with enrollment from November 2011 through November 2012. Whereas GEMS-1 studied children under five years of age diagnosed with mid-to-severe diarrhea (MSD), in all countries but Kenya GEMS-1A compared cases of MSD with cases of less-severe diarrhea (LSD) in children over the age of five.

In Kenya, GEMS-1A assessed the relationship between HIV and moderate and severe diarrhea (MSD) among children 0-59 months of age living in a setting of high HIV prevalence. Rather than comparing MSD and LSD, the Kenya study enrolled only MSD cases and matched controls in studying the effect of HIV in relation to MSD.