Macular degeneration
- Age-sex splitting
- MR-BRT Sex Ratio Analysis
- Age Pattern analysis
- MR-BRT bias correction analysis for Alternative Case Defintion / Method
- Split into moderate and severe vision loss
- Squeeze into severity-specific vision loss envelope
- Comorbidity correction (COMO)
- Dismod-MR 2.1
Major depressive disorder
- MR-BRT analysis on change in prevalence during COVID-19 pandemic compared to before the pandemic
- Age-sex splitting
- MR-BRT Sex Ratio Analysis
- MR-BRT Bias Correction Analysis for Alternative Case Defintion / Method
- Comorbidity correction (COMO)
- Dismod-MR 2.1
- Mapping of EQ5D to SF-12
- Mapping to SF-12 GBD disability weight
- Regression to estimate disability weights by cause in survey respondents controlling for comorbidity
- Estimated suicide rates attributable to MDD
Malaria (Africa)
- Geospatial ITN coverage model (Africa)
- Geospatial effective treatment rate model (Africa)
- Diagnostic sensitivity model (baseline) (Africa)
- Age-prevalence model (baseline) (Africa)
- Diagnostic sensitivity model (post-baseline) (Africa)
- Age-prevalence model (post-baseline) (Africa)
- Intervention effects model (post-baseline) (Africa)
- PfPR\incidence conversation model (Africa)
- Conversion to prevalence (Africa)
- Short vs. long-term outcomes (Africa)
- Severity splits (Africa)
- Disability weights (Africa)
- DisMod-MR 2.1 (Africa)
- Comorbidity correction (COMO) (Africa)
Malaria (outside of Africa)
- National-level treatment-seeking model (outside of Africa)
- Adjustments for treatment seeking % and underreporting % (outside of Africa)
- Masking non-risk areas based on environmental factors (pixel) (outside of Africa)
- PfPR\incidence conversation model (outside of Africa)
- Diagnostic sensitivity model (polygon+point) (outside of Africa)
- Age-prevalence model (polygon+point) (outside of Africa)
- Conversion to prevalence (outside of Africa)
- Short vs. long-term outcomes (outside of Africa)
- Comorbidity correction (COMO) (outside of Africa)
- DisMod-MR 2.1 (outside of Africa)
- Severity splits
- Disability weights
Maternal disorders
- crosswalk alternative definitions to reference
- Adjustment of clinical data based on literature studies
- Adjustment of claims data based on inpatient and literature studies for other maternal infections model
- Adjustment of clinical data based on surveillance
- Adjustment of PPH and APH only to all hemorrhage
- Adjustment of PIH and preeclampsia to all HDoP
- Adjustment of clinical data based on literature studies for eclampsia model
- Adjustment claims data based on inpatient data for sever preeclampsia model
- Adjustment of inpatient based on claims data
Measles
- Age-sex splitting (based on cause of death data)
- Mixed effects regression
- Prevalence = incidence * duration
- Covid impacts
- Severity splits, assuming 50% are moderate and 50% are severe measles
- Comorbidity correction (COMO)
Meningitis
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- Adjustment for readmissions and from primary code to all code based on claims data
- MR-BRT sex splitting
- MR-BRT crosswalk claims and surveillance to adjusted inpatient data
- Age splitting
- DisMod-MR 2.1
- Regression of ln(GDP) and proportion of long-term outcome
- For each of bacterial & viral: apply proportion of long-term outcome
- Global meta-analyzed value of proportion of long-term outcome
- Proportions of specific long-term outcomes, amongst those with any long-term outcome
- For bacterial & viral: apply proportion of long-term outcome type to incidence of long-term outcome
- DisMod ODE
- Epilepsy envelope squeeze
- Calculate EMR
- Proportions of sequelae given long-term outcome
- Apply proportion of sequela type to incidence of long-term outcomes
- For each sequela, sum bacterial & viral YLDs
- Apply etiology-specific cause fractions to unadjusted YLD by sequela
- Apply ratio of viral to bacterial meningitis to bacterial meningitis envelope
- Central squeeze and severity splits
- Comorbidity correction (COMO)
- LRI etiology
- MR-BRT to estimate CFR as a function of HAQ and pathogen
- Death data: divide deaths/CFR to get cases. Case data: untransformed
- Age- and sex- split data by pathogen
- Estimate aetiology fractions: multinomial estimation of partial and complete observations (MEPCO)
- Rescale these etiology fractions to account for lower incidence of sequela in viral
Motor neuron disease
- Age-split broad-age data-points
- MR-BRT Sex Ratio Analysis
- Split both-sex data
- Study design bias analysis in MR-BRT
- Adjust non-reference data
- Dismod-MR 2.1
- Comorbidity correction (COMO)
- Format codes Map to modeling causes
- Convert claims to cases Apply duration window Apply age and sex restrictions Aggregate
- Meta-analyses
- Severity split
