Non-rheumatic calcific aortic valve disease
- Age-sex splitting
- Asymptomatic proportion model
- Treatment proportion model
- Severity split
- Dismod MR 2.1
- Comorbidity correction (COMO)
- Heart failure severity split model
- Disability weights for each sequela
Non-rheumatic degenerative mitral valve disease
- Age-sex splitting
- Asymptomatic proportion model
- Treatment proportion model
- Severity split
- Dismod MR 2.1
- Comorbidity correction (COMO)
- Heart failure severity split model
- Disability weights for each sequela
Non-rheumatic valvular heart disease
Nonfatal Adult Syphilis Estimation
- Data Adjustment: Sex-split, crosswalk, age-split (SS)
- Data Adjustment: inpatient to claims (ATS)
- Estimate Disease Duration (SS)
- Dismod-MR 2.1
- Comorbidity correction (COMO)
- Severity splits
- Adjustment from primary code to all code for both inpatient and outpatient encounters based on claims data
Nonfatal Congenital Syphilis Estimation
- number of CS cases at 28days and at birth
- Vertical Transmission Meta-analyses
- Sequela Meta-Analyses
- percent symptomatic cases by y-a-s-l
- Dismod-MR 2.1
- Comorbidity correction (COMO)
Nonfatal Injuries
- LTD
- EN
- Pipeline
- Derive outpatient incidence using outpatient coefficent
- Incidence by Ecode
- Apply incidence-to-mortality ratios to fatal discontinuities and state actor violence deaths
- Apply incidence E\N matrices (if multiple N-codes, assign the most severe)
- (% treated*treated duration) + (% untreated*untreated duration)
- Calculate fraction of incidence that is long-term
- Translate SMR to excess mortality
- Calculate prevalence (incidence *duration)
- Apply short-term disability weights
- Upload results to epi database
- Crosswalking
- EMR
Obstetric fistula
- Age-sex splitting
- proportion vesicovaginal and rectovaginal
- Severity Splits
- Geographic exclusions
- Comorbidity correction (COMO)
- DisMod-MR 2.1
Onchocerciasis
- Extrapolation of all case prevalence and sequelae
- Combine acute and chronic skin disease level 2
- Multiply visual impairment and blindness by random value normally distributed with mean zero and standard deviation 0.1 to add uncertainty
- Multiply visual impairment estimates by a random value to generate moderate vision impairment, then subtract resulting estimates from visual impairment to obtain estimates of severe vision impairment
- Re-calculate prevalence
- Transform to logit space - logit(prevalence)
- Add uncertainty due to nod-mf conversion for OCP countries
- Normalize draws
- Add time trend uncertainty
- Re-expand normalized draws to adjusted scale
- Model population at risk in each focuse using a Poisson model. Covariates: year splines
- Model prevalence of onchocerciasis in the Americas among the population at risk in each focus using a glm model with binomial family, logit link, no intercept term and random effects on a combined foci cariable. Covariates: focie indicator variable, years since MDA start, age splines
- Sum cases across GBD location-years and divide by population
- Adjust prevalence in foci estimates by population at risk to get case total by foci
- Split sequelae using all-age all-sex global sequelae ratios in Africa estimates
- Estimate prevalence of asymptomatic onchocerciasis
- YLD calculation
- Comorbidity Correction
Opioid use disorders
- Computing excess mortality from available incidence & CSMR data
- Case definition adjustment
- Age-sex splitting
- IHME-indirect calculation
- Comorbidity correction (COMO)
- Dismod-MR 2.1
- Mapping of EQ5D to SF-12
- Regression to estimate disability weights by cause in survey respondents controlling for comorbidity
- Mapping to SF-12 GBD disability weight
Oral Deciduous Caries
- Calculation of D\DMF ratio for all data where both measures exist
- Calculation of incidenceas the DMF increment between adjacent ages
- Conversion of DMF scores to dental caries prevalence using D\DMF ratio calculated from the same row, study, or location
- Meta-analysis of percent of conditions associated with edentulism and severe tooth loss
- Severity splits
- Permanent/Deciduous Carries processing
- Uploading dental data/Age-sex splitting
- Generate/apply crosswalks
- Uploading crosswalks
- Saving processed dental models
- Comorbidity correction (COMO)
- Dismod-MR 2.1; excess mortality rate set to 0
Oral Edentulism
- Meta-analysis of percent of conditions associated with edentulism and severe tooth loss
- Severity splits
- Edentulism processing
- Uploading dental data/Age-sex splitting
- Generate/apply crosswalks
- Uploading crosswalks
- Saving processed dental models
- Comorbidity correction (COMO)
- Dismod-MR 2.1
