Tetanus
- Comorbidity correction (COMO)
- DisMod-MR 2.1
- Appy percent mild, moderate, severe
- Incidence = Mortality\CFR
- Incidence of survival from neonatal tetanus
- Prevalence = incidence * duration
- severity splits as in neonatal encephalopathy
- Severity splits
Trachoma
- Comorbidity correction (COMO)
- Mixed-effects model
- Multiply proportion by blindness envelope
- Multiply proportion by low vision envelope
- Principal components analysis (PCA)
- Split into moderate and severe vision loss
- Squeeze into severity-specific vision loss envelope
Trichuriasis
- Comorbidity Correction
- Prepare data for ST-GPR
- ST-GPR
- Compute age-specific ratios; apply ratio to ST-GPR output
- Compute proportion of cases that belong to health states
- Apply health state proportions to overall hookworm envelope
- Estimate prevlanece of severe wasting due to trichuriasis
- Estimate prevalence of asymptomatic trichuriasis
- Data preparation
- Dismod-MR 2.1
- YLD Calculation
Tuberculosis
- Bayesian meta-regression to pool RR per mm of induration
- Comorbidity correction (COMO)
- Compute % individuals in each category of induration mm
- Compute risk weighted prevalence of latent TB infection (LTBI)
- Inflate prevalence for extra-pulmonary TB
- Divide by risk-weighted LTBI prevalence
- Predict MI ratio-based incidence (
- Divide incidence by risk-weighted LTBI prevalence
- Divide CSMR by risk-weighted LTBI prevalence
- Compute EMR priors based on CSMR, incidence & prevalence
- Calculate prevalence and incidence among the entire population
- Mixed effects regression to predict location-year specific %HIVTB among TB cases
- Apply %HIVTB to TB all forms by location\year
- Age split HIVTB prevalent & incident cases by HIV prevalence
- Calculate proportions of MDR-TB in HIV-TB cases
- Apply MDR-HIV-TB proportions to HIV-TB cases
- Apply super-region level proportions of XDR-TB in MDR-TB cases to all MDR-HIV-TB cases
- Subtract XDR-HIV-TB from MDR-HIV-TB
- Subtract MDR HIVTB from HIVTB
- Subtract HIVTB from TB all forms
- Compute proportions of retreated cases among all TB cases
- Compute proportions of MDR-TB among new TB cases w/DST results
- Compute proportions of MDR-TB among retreated TB cases w/DST results
- Space-time Gaussian Process Regression
- Compute proportions of new cases among all TB cases
- Computed weighted average of the proportions of new and retreated cases w/MDR-TB
- Calculate proportions of MDR-TB in TB no-HIV cases
- Apply MDR-TB proportions
- Subtract MDRTB no-HIV from TB no-HIV
- Calculate super-region level proportions of XDR- TB among MDR-TB cases
- Apply super-region level proportions of XDR-TB among MDR-TB cases to all MDR-TB cases
- Subtract XDR-TB no-HIV from MDR-TB no-HIV
- DisMod-MR 2.1
Typhoid & Paratyphoid
- Comorbidity correction (COMO)
- DisMod model of incidence
- DisMod model of proportion
- Diagnostic sensitivity adjustment
- Incidence split
- Metaanalysis of blood culture sensitivity
- Rescaling to sum to 1
- Severity splits
Upper Respiratory Infections
- % mild, moderate, severe
- Comorbidity correction (COMO)
- Age sex splitting
- Converting period to point prevalence
- DisMod-MR 2.1
- Severity splits
Urticaria
- Comorbidity correction (COMO)
- Dismod-MR 2.1
- Age-sex splitting
- Meta-analysis of % mild and severe Urticaria
- Severity splits
Uterine fibroids
- Comorbidity correction (COMO)
- Adjustment from primary code to all code based on Claims data
- Meta-analysis of % mild, moderate, severe uterine fibroids
- Dismod-MR 2.1
- Severity splits
Varicella and herpes zoster
- Comorbidity correction (COMO)
- DisMod-MR 2.1
- Assume all varicella cases are mild
- Population incidence rate calculation
- Prevalence calculation
Vascular intestinal disorders
- Calculate correction factor
- Comorbidity correction (COMO)
- Convert claims to incident cases, Apply age and sex restrictions, Aggregate
- Convert inpatient encounters to incident cases, Correct for only having primary diagnosis, Apply age and sex restrictions, Aggregate
- DisMod-MR 2.1
- Format codes, Map to modeling causes
Viral skin diseases
- Adjustment from primary code to all code based on Claims data
- Age-sex splitting
- Comorbidity correction (COMO)
- Dismod-MR 2.1
- Meta-analysis of % mild and severe Viral skin diseases
- Severity splits
Visceral leishmaniasis
- Comorbidity correction (COMO)
- ST-GPR
- Age-sex splitting
- Presence and underreporting adjustment
- Sequela split
