Research by the Global Burden of Disease Health Financing Collaborator Network produced retrospective health spending estimates for 1995-2021 for 204 countries and territories. The estimates cover total health spending, health spending disaggregated by source into three domestic financing source categories (government, out-of-pocket, and prepaid private), and development assistance for health (DAH). Domestic health spending source data came primarily from the WHO’s Global Health Expenditure Database (GHED). DAH data came from a diverse set of sources, including program reports, budget data, national estimates, and National Health Accounts (NHAs). The resulting estimates were used to forecast GDP and prospective health spending estimates for 2022-2050. Estimates are reported in constant 2022 United States Dollars, constant 2022 purchasing power parity adjusted (PPP) dollars, and as a percent of gross domestic product.