Research by the Global Burden of Disease Health Financing Collaborator Network produced projected health spending estimates for 2022-2050 for 204 countries and territories. The estimates cover total health spending, health spending disaggregated by source into three domestic financing source categories (government, out-of-pocket, and prepaid private), and development assistance for health (DAH). Retrospective health spending estimates for 1995-2022 and key covariates (including GDP per capita, total government spending, total fertility rate, and fraction of the population older than 65 years) were used to forecast GDP and health spending through 2050. Estimates are reported in constant 2022 US dollars, constant 2022 purchasing-power parity-adjusted (PPP) dollars, and as a percent of gross domestic product.