Research by the Global Burden of Disease Health Financing Collaborator Network estimated HIV/AIDS spending for 137 low- and middle-income countries for 2000-2016. The estimates cover HIV/AIDS spending disaggregated by source into three domestic financing source categories (government, out-of-pocket, and prepaid private) and development assistance for health (DAH). Spending is also disaggregated by function, including care and treatment, prevention, and other spending. Domestic HIV/AIDS spending by source and function was estimated based on five major data sources: the AIDSinfo online database, Global Fund concept notes and proposals, National Health Accounts (NHAs), National AIDS Spending Assessments, and the AIDS data hub. Development assistance for HIV/AIDS data were drawn from IHME's 2018 Development Assistance for Health Database. Estimates are reported in constant 2018 United States dollars.