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India - Kolkata Global Enteric Multicenter Study 2007-2011


General Info
Original or alternative title 
Global Enteric Mutli-Center Study / GEMS-1
India (IND)
West Bengal
Coverage type 
Time period covered 
12/2007 - 03/2011
Series or system 
Global Enteric Multicenter Study (GEMS)
Data type
  • Exam
  • Health facility
  • Household
  • Individual
  • Interview

The Global Enteric Multicenter Study (GEMS-1) was a multi-country case-control study of diarrheal disease in children under five years of age. Study sites in each country were required to have access to some type of demographic surveillance system for tracking participants and at least one healthcare facility that provided care to children of that population with diarrhea. A Health Utilization and Attitudes Survey (HUAS) of 1,100 households in the selected population was conducted in each country prior to starting the case-control portion of the study, in which 660 children with mild-to-severe diarrhea (cases) and a matching 660 of children without diarrhea (controls) were enrolled in the study in each of 3 age strata (0-11, 12-23, and 24-59 months). Participants were examined at initial enrollment and again after approximately 60 days; anthropometric measurements were collected at both the enrollment exam and followup home visit, and stool samples were collected at the enrollment exam.

Suggested citation 
Center for Vaccine Development (Chile), Center for Vaccine Development, University of Maryland, Centers for Disease Control and Prevention (CDC), Department of Medical Microbiology and Immunology, Göteborg University, International Vaccine Institute, National Institute of Cholera and Enteric Diseases (India), Perry Point Cooperative Studies Program Coordinating Center, U.S. Department of Veterans Affairs, School of Medicine, University of Virginia, University of Chile. India - Kolkata Global Enteric Multicenter Study 2007-2011. Baltimore, MD, United States of America: Center for Vaccine Development, University of Maryland.